John Siracusa, who I've drawn before, is a longtime favourite podcaster of mine. I first heard him on Hypercritical and have followed him through Neutral to ATP. He's a picky guy (by picky, I mean two whole episodes on video game controllers and a 3 hour conversation about Goodfellas picky) who talks a lot of sense.
Merlin Mann's Back to Work was incredibly helpful to me when I had a job I really hated. I don't think I'd have had the confidence to go full-time as an illustrator without listening to episodes like Failing with Style on my miserable morning cycle to the office. His other podcasts, You Look Nice Today and Roderick on the Line are also great.
John and Merlin have occasionally talked about things like Totoro and Toy Story over on the incomparable, um, The Incomparable podcast, but having them together on the regs is gonna be a treat. Cheers to the folks at Relay for making it happen (co-founders Myke and Stephen seem like the nicest dudes in the world. I'm stoked for them).
Reconcilable Differences is pencilled in for 10 episodes over the summer and episode 1, We All Ruined It Together is a brilliant start. I'm already hoping that they'll keep going longer. Give it a listen.
ps. There's a big version of the artwork over here.